Orf3a -> Hops_Complex_complex LPS_TNF___IL_1_complex -> IKBKG_IKBKB_CHUK_complex TLR4 -> LPS_TLR4_MYD88_complex IRF6 -> LPS_TLR4_MYD88_complex sa143_MYD88_cytoplasm -> LPS_TLR4_MYD88_complex IKBKG_IKBKB_CHUK_complex -> P65_P015_complex sa83_E_cytoplasm -> P65_P015_complex TRAF3 -> P65_P015_complex Orf3a -> P65_P015_complex TRIM30a_TRIM38_complex -| TAB2_TAB3_TAK1_complex sa38_TRAF6_cytoplasm -> TAB2_TAB3_TAK1_complex ssRNA_rna -> TLR7_8_9_complex TAB2_TAB3_TAK1_complex -> NEMO_IKKA_IKKB_complex TRIM22 -| NEMO_IKKA_IKKB_complex TRIM29 -| NEMO_IKKA_IKKB_complex TRIM14_TRIM23_complex -> NEMO_IKKA_IKKB_complex TRIM27_TRIM21_complex -| NEMO_IKKA_IKKB_complex NFKB1 -> NFKB1_NFKNIA_complex NFKBIA_phosphorylated_ubiquitinated_ubiquitinated_ubiquitinated -> NFKB1_NFKNIA_complex CACTIN -| NFKB1_NFKNIA_complex Orf3a -> TRIM59 ORF8b -> NLRP3 TRAF3 -> PYCARD_ubiquitinated_ubiquitinated_ubiquitinated Orf3a -> PYCARD_ubiquitinated_ubiquitinated_ubiquitinated TICAM1 -> TRAF3 PYCARD_ubiquitinated_ubiquitinated_ubiquitinated -> CASP1 NLRP3 -> CASP1 sa101_TRAF6_cytoplasm -> sa38_TRAF6_cytoplasm sa49_MYD88_cytoplasm -> sa38_TRAF6_cytoplasm sa52_TRIM38_cytoplasm -| sa38_TRAF6_cytoplasm TRIM23 -> sa38_TRAF6_cytoplasm TLR3 -> TICAM1 sa50_TRIM38_cytoplasm -| TICAM1 TLR7_8_9_complex -> sa49_MYD88_cytoplasm BTRC -> NFKBIA_phosphorylated_ubiquitinated_ubiquitinated_ubiquitinated NEMO_IKKA_IKKB_complex -> NFKBIA_phosphorylated_ubiquitinated_ubiquitinated_ubiquitinated TRIM9 -| BTRC Orf3a -> S TAB2_TAB3_TAK1_complex -> SERPINF2 sa127_IL1b_cytoplasm -> sa92_IL1b_cytoplasm CASP1 -> sa92_IL1b_cytoplasm sa90_E_cytoplasm -> sa92_IL1b_cytoplasm P65_P015_complex -> sa92_IL1b_cytoplasm double_stranded_RNA_rna -> TLR3 LPS_TLR4_MYD88_complex -> sa101_TRAF6_cytoplasm P65_P015_complex -> sa127_IL1b_cytoplasm TRIM39 -> CACTIN TRIM59 -| sa143_MYD88_cytoplasm SERPINF2 -> IFNB1 $BTRC: !TRIM9 $CACTIN: TRIM39 $CASP1: (PYCARD_ubiquitinated_ubiquitinated_ubiquitinated & NLRP3) $Hops_Complex_complex: Orf3a $IFNB1: SERPINF2 $IKBKG_IKBKB_CHUK_complex: LPS_TNF___IL_1_complex $LPS_TLR4_MYD88_complex: ((TLR4 & IRF6) & sa143_MYD88_cytoplasm) $NEMO_IKKA_IKKB_complex: ((((TAB2_TAB3_TAK1_complex | TRIM14_TRIM23_complex) & !TRIM22) & !TRIM29) & !TRIM27_TRIM21_complex) $NFKB1_NFKNIA_complex: ((NFKB1 & NFKBIA_phosphorylated_ubiquitinated_ubiquitinated_ubiquitinated) & !CACTIN) $NFKBIA_phosphorylated_ubiquitinated_ubiquitinated_ubiquitinated: (BTRC | NEMO_IKKA_IKKB_complex) $NLRP3: ORF8b $P65_P015_complex: ((IKBKG_IKBKB_CHUK_complex & sa83_E_cytoplasm) | ((TRAF3 | IKBKG_IKBKB_CHUK_complex) | Orf3a)) $PYCARD_ubiquitinated_ubiquitinated_ubiquitinated: (TRAF3 | Orf3a) $S: Orf3a $SERPINF2: TAB2_TAB3_TAK1_complex $TAB2_TAB3_TAK1_complex: (sa38_TRAF6_cytoplasm & !TRIM30a_TRIM38_complex) $TICAM1: (TLR3 & !sa50_TRIM38_cytoplasm) $TLR3: double_stranded_RNA_rna $TLR7_8_9_complex: ssRNA_rna $TRAF3: TICAM1 $TRIM59: Orf3a $sa101_TRAF6_cytoplasm: LPS_TLR4_MYD88_complex $sa127_IL1b_cytoplasm: P65_P015_complex $sa143_MYD88_cytoplasm: !TRIM59 $sa38_TRAF6_cytoplasm: (((sa49_MYD88_cytoplasm | TRIM23) & sa101_TRAF6_cytoplasm) & !sa52_TRIM38_cytoplasm) $sa49_MYD88_cytoplasm: TLR7_8_9_complex $sa92_IL1b_cytoplasm: (((CASP1 | sa90_E_cytoplasm) | P65_P015_complex) & sa127_IL1b_cytoplasm)